Flight-readiness triage for DNA assay hardware
Should this mutation
get an oligo, a photodiode and a launch slot?
ORBITGENE pulls a real protein substitution from UniProt and its coding sequence from RefSeq, scores it against your own assay optics and probe thermodynamics, prices the radiation your sample buffer will absorb in orbit, and seals the decision into a hash-chained record. Every number on screen is shown with the evidence behind it.
- Factors
- 6weighted and itemised
- Seal
- SHA-384per-record hash chain
- Sources
- 4UniProt, RefSeq, ClinVar, NOAA
- Agent tools
- 9MCP JSON-RPC 2.0
Live readiness read
Pick a gene to score a real substitution
The plate
One well is one scored record. Yours is empty until you add to it.
- Cleared
- Hold
- Ground only
- Empty
Job 1
A lab lead can price a substitution before ordering an oligo
Enter a real UniProt residue and the engine computes the codon change, the nearest-neighbour melting shift for the probe you would actually buy, and the photon budget of your own detector. You order fewer dead probes.
Job 2
A payload engineer can see whether the readout survives the flight
Move shielding, orbit and mission length and the radiation budget re-derives the dose, the expected single-event upsets in the sample buffer and the number of redundant readouts you actually need.
Job 3
A collaborator can check a decision without an account
Every create, update, decision and retirement appends to a SHA-384 chain. Share a record with a token and your colleague replays the chain from its genesis value and sees the same verdict.
Real sequences
Protein from UniProt, coding DNA sliced from the annotated CDS in the RefSeq GenBank record.
Real optics
Photon transfer from your emitter, responsivity, dark current, gain and ADC resolution.
Real sky
Planetary K index, GOES X-ray class and proton flux read live, with a labelled sealed fallback.
Real audit
Every mutation appends a SHA-384 sealed event. Deletions leave a replayable tombstone.
Safety and scope
ORBITGENE is a research and teaching instrument. It is not a diagnostic device and nothing here is clinical advice. A score describes whether a substitution is worth an assay and a flight slot, not whether a person has a condition.
Variant annotations are read from public databases and inherit their curation. Verify anything that matters against ClinVar, the primary literature and a clinical geneticist before acting on it.